Micro X-ray Spectral Analysis and Comprehensive In Vivo Study of Modified Titanium Implants.

We developed a technique for the complex modification of the surface of dental implant made of VT1-0 titanium that included sequential mechanical treatment and irradiation with powerful ion beams. The chemical composition and physical properties of the surface of titanium implants (VT1-0 grade) sandblasted with subsequent acid etching, as well as subjected to complex treatment (sandblasting and irradiation with powerful ion beams) were evaluated using micro-X-ray spectral analysis. In in vivo experiments, osseointegrative properties of the implants subjected by these treatments were compared. Microrentgenospectral analysis of dental implants subjected to irradiation with powerful ion beams revealed higher indicators of surface cleanliness; in in vivo experiments, morphometric analysis also demonstrated high osseointegrative properties.

Application of Barophoresis in Chronic Generalized Periodontitis: a Mathematical Substantiation.

The aim of the study was to evaluate the use of barophoresis for the delivery of liquid-air drug substances to the gums using a mathematical model of the interaction of the drug mixture with periodontal tissues. Materials and Methods: The solution to the problem was preceded by generation of a geometric CAD model of the device and nozzle for barophoresis, including the nozzle and injector geometry. The Ansys SpaceClaim software package was used to generate the CAD geometry. Results: When solving the problem of finding the optimal distance from the nozzle to the gum surface, the numerical modeling showed that at a distance of 5 mm, the volume fraction of liquid in the mixture is 18-20%. The mixture actually breaks through the gum, filling 0.8 mm of the gum thickness and spreading symmetrically to the sides at a distance of up to 3 cm, forming a cavity. At a distance of 10 mm from the nozzle to the gum surface, the liquid volume fraction in the mixture close to the gum lies in a narrow range of values of 5 to 7%. The mixture touches the surface of the gums, penetrating slightly - at a distance of 0.30-0.45 mm. At a distance of 15 mm from the nozzle to the gum surface, the volume fraction of liquid in the mixture near the gum lies in the range of 2-5%. The mixture slightly touches the gum surface, getting inside at a distance of up to 0.2 mm, having practically no effect on the gum. Conclusion: The developed mathematical model confirmed the feasibility of application of barophoresis in the treatment of chronic generalized periodontitis. The optimal distance from the nozzle to the surface should be considered to be 10-15 mm. This distance is safe and allows the drug delivery to a depth of 0.45 mm.

Biocompatibility and Bioresorption of 3D-Printed Polylactide and Polyglycolide Tissue Membranes.

We studied biocompatibility and bioresorption of 3D-printed polylactide and polyglycolide tissue membranes. Ultrasound microscopy and histological examination showed that membranes fabricated of a copolymer of lactic and glycolic acids in a mass ratio of 1:9 are bioresorbed and have good biocompatibility with soft tissues (connective tissue, adipose tissue, and epithelium). An important feature of the copolymer membranes, which differs them from pure polylactide membranes, is the formation of a thin fibrous capsule that did not interfere its destruction by the mechanism of hydrolytic resorption.

[Dental implants in complex oral rehabilitation in patients with class III occlusion and partial teeth loss].

To prove the efficiency of dental implantation in complex treatment of patients with class III malocclusion and partial teeth loss. Nine patients aged 18-35 years with class III malocclusion and partial teeth loss were included in the study. All patients received two-step treatment involving orthodontic correction with two-step implantation and provisional restorations placement followed by orthognatic surgery procedure. The patients were followed-up for three years with no recurrent malocclusion or implant failure revealed, thus proving dental implantation to be useful tool in complex oral rehabilitation of patients with class III malocclusion and partial teeth loss.